Repeatability and Reproducibility of Pancreatic Proton Density Fat Fraction Measurements Using Manually Drawn Regions of Interest

Motivation: Determination of repeatability and reproducibility is vital to interpreting and determining measurable change of intra organ fat, specifically in small organs like the pancreas. Goal(s): The goal of this study is to determine if intra-user repeatability and inter-user reproducibility coefficients of manually drawn ROIs on pancreatic fat. Approach: The approach of this study was to compare manually drawn ROIs within the pancreas between two users and within a single user. Results: Results indicate that repeatability and inter-user reproducibility of manually drawn ROIs to determine the MRI measured pancreatic fat fraction were consistent within and across users. Impact: The repeatability and inter-user reproducibility of manually drawn ROIs to determine the MRI measured pancreatic fat fraction yielded consistent measures both within and across users.