Nonparametric evaluation of diffusion regimes in brain tumours and associated diffusion hyperintensities

Motivation: To investigate tumour-associated diffusion hyperintensitiesGoal(s): Might provide some insight into tumour environment leading to restricted diffusion. Approach: Extended diffusion range, with b-values from 0 to 10000 and two echo times, allowing for NNLS decomposition of diffusion spectra and T2 mapping. Results: Restricted diffusion characterised. Impact: Possibly relevant to tumour cell migration and associated changes in the extracellular matrix.