Investigating ASL-MRI as a Complementary Modality for 18F-FDG PET in Identifying Mesial Temporal Lobe Epilepsy Laterality in Grey Matter

Motivation: Using non-invasive ASL-MRI as a substitute of 18F-FDG PET for identification of epileptogenic zone in mTLE patientsGoal(s): This study aims to check if there is a correlation between the CBF of ASL-MRI and metabolic data from 18F-FDG PET. Approach: Brain division into 12 ROIs, including key areas like the amygdala and hippocampus, used BASIL and FSL tools for CBF and SUVr extraction. Used Pearson's and Spearman's rank correlation of SPSS for correlation analysis. Results: Significant CBF and SUVr correlations in middle temporal gyrus, hippocampus, and superior temporal found in mTLE patients. Impact: This study affects mTLE patients' accurate and rapid epileptogenic foci location.