MRI-based analysis of the blood flow in the left ventricle: 2D geometry-prescribed Cine-MRI based model versus 4D-Flow CMR

Motivation: 4D-Flow CMR allows to analyze 3D blood flow patterns in the left ventricle, however it requires time-consuming acquisitions and complex pre and post-processing. Goal(s): The objective is to develop a method to analyze blood flow patterns in the left ventricle without these disadvantages. Approach: Using Cine-MRI and patient-specific modelling techniques, we introduced a new and semi-automated method to simulate the blood flow inside the left ventricle. Accuracy of the developed method was evaluated by comparing the results to 4D-Flow CMR analysis performed on one healthy subject. Results: Both techniques showed similar blood flow patterns and comparable hemodynamics parameters. Impact: This patient-specific model is a relatively simple and time-saving method allowing blood flow analysis in the left ventricle based on Cine-MRI acquisition. It may be used to characterize blood flow in patients with heart disease at rest or under stress.