Accelerated atrial pacing reduces left-heart filling pressure: a combined clinical-computational study
Accelerated pacing acutely reduces left-heart filling pressure in patients undergoing AF catheter ablation and computer simulations with HFpEF features, suggesting it as a potential therapeutic strategy to alleviate congestion symptoms. Virtual HFpEF patient cohorts hypothesize that AV sequential pacing may further optimize this therapy's beneficial effects.
Authors
- Richard Cornelussen (ORCID: https://orcid.org/0000-0002-6504-3314)
- Nick van Osta (ORCID: https://orcid.org/0000-0002-8927-9110)
- Jesse Rijks (ORCID: https://orcid.org/0000-0001-5136-4830)
- Joost Lumens (ORCID: https://orcid.org/0000-0001-8129-7384)
- Kevin Vernooy (ORCID: https://orcid.org/0000-0002-8818-5964)
- Frits W. Prinzen (ORCID: https://orcid.org/0000-0001-8917-9032)
- Johan van Koll (ORCID: https://orcid.org/0009-0000-7892-7074)
- Dominik Linz (ORCID: https://orcid.org/0000-0003-4893-0824)
- Vanessa P. M. van Empel (ORCID: https://orcid.org/0000-0002-6864-0296)
- Tammo Delhaas (ORCID: https://orcid.org/0000-0001-6897-9700)
- Justin Luermans (ORCID: https://orcid.org/0000-0001-9598-2286)
- Tim van Loon (ORCID: https://orcid.org/0009-0009-4187-8948)
- Joey Wolffs
Institutions
- Bakken Museum (US)
- University Medical Center (US)
- Maastricht University (NL)
- Medtronic (Netherlands) (NL)
Publication Details
- Journal
- European Heart Journal
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1093/eurheartj/ehae718
- Citations
- 19
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 7.64