Evaluation of Amide Proton Transfer-Weighted Imaging and T2 mapping for preoperative risk stratification of endometrioid adenocarcinoma

Motivation: Preoperative risk stratification of endometrioid adenocarcinoma (EA) impacts the choice of operative modality and prognosis of patients. Goal(s): We aimed to perform an accurate and non-invasive preoperative risk stratification method for EA by MRI sequences. Approach: APTw imaging as well as T2 mapping were included in this study. Results: The APTw and T2 values showed significant differences between the low- and non-low-risk groups. Combining APTw with T2 mapping achieved the highest diagnostic efficacy in the preoperative risk stratification. Impact: This suggested that the integrated use of APTw and T2 mapping can be an effective method for the preoperative risk assessment of EA.