Prediction value of DWI-ASPECTS and HR-VWI to evaluate the response of patients with acute ischemic stroke

Motivation: The predicted ability of High-resolution vessel wall imaging (HR-VWI) combined with diffusion-weighted imaging (DWI) in acute ischemic stroke (AIS) patients based on the simplified modified Rankin Scale questionnaire（smRSq）remains unknown. Goal(s): The purpose is to analyze AIS patients by obtaining HR-VWI and DWI information for further providing the information for endovascular therapy. Approach: Patients are grouped by smRSq including the good response group and the poor. The characteristics of plaque and DWI are analysed for comparing between the two groups. Results: Severe stenosis, high normalized wall index, plaque enhancement, T1WI high signal and low ASPECTS were risk factors of poor response (all P<0.05). Impact: The combination of HR-VWI and ASPECTS can assist clinical in adopting different rehabilitation management methods for patients.