MRI-conditional deep brain stimulation (DBS) implants: a new engineered design for enhanced safety

Motivation: Currently, patients with Deep Brain stimulation (DBS) implants cannot leverage the diagnostic potential of Magnetic Resonance Imaging (MRI) as traditional metal-based leads pose several safety concerns. Goal(s): We propose a new technology for manufacturing DBS microwires that ensures their safe operation with MRI up to 3T. Approach: Through the development of a metamaterial-based design, we have engineered microwires that effectively partially reflect RF-induced current, thereby reducing Specific Absorption Rate (SAR), tip heating, and associated artifacts. Results: Our manufactured microwires demonstrated minimal tip heating in both 1.5T and 3T MRI scanners when compared to standard wires. Impact: This innovative design facilitates safe MRI imaging for individuals with DBS implants, marking a pivotal advancement in the study of neural mechanisms involved in medically refractory pathological conditions, such as Parkinson’s disease.