Hybrid Multidimensional MRI: Demonstrating Repeatability in Non-Invasive Prostate Cancer Tissue Characterization

Motivation: Validate the consistency and reliability of Hybrid Multidimensional MRI (HM-MRI) through repeatability assessments. Goal(s): Evaluate the repeatability of HM-MRI in prostate tissue characterization and its diagnostic accuracy for prostate cancer. Approach: Our approach consists on performing dual HM-MRI scans with a one-week interval to assess measurement consistency and diagnostic accuracy of HM-MRI biomarkers. Results: The results indicate high reproducibility of HM-MRI metrics, evidenced by strong inter-class correlation coefficients, with consistent tissue composition measurements across initial and repeat scans, and robust diagnostic performance of HM-MRI parameters in prostate cancer detection. Impact: The findings of this study highlights the potential of HM-MRI as a reliable tool for prostate cancer diagnosis, paving the way for non-invasive clinical applications and inspiring further research into its utility in other diagnostic imaging techniques.