Translating multiparametric, quantitative MRI from 3T to 7T: A preliminary study.

Motivation: Quantitative MRI at clinical strengths is well-established, yet RF inhomogeneity at ultrahigh-field strength, such as 7T, complicates tissue-specific measurement. Goal(s): To extend quantitative water content mapping from clinical to ultrahigh-field MRI. Approach: We utilize a modified variable flip angle method to acquire high-resolution parametric maps at 7T within 7.5 minutes. Results: Method validity is affirmed by comparing water content and relaxometry data from a healthy cohort against 3T benchmarks and reported literature. Impact: This technique paves the way for advanced brain tissue analysis at ultrahigh-field MRI (7T), crucial for accurate neurological assessment.