Accuracy of PIRADS 2.1 scoring system to Screen Prostate Cancer in a Ugandan population

Motivation: Prostate cancer is highly incident in Africa. Early screening and detection is recommended to lower this rate. BpMRI and PIRADS are used to detect, stage prostate cancer. The accuracy of PIRADS in an African population hasn’t been determinedGoal(s): Determine the accuracy of PIRADs to screen Prostate cancer in an African populationApproach: We assessed the accuracy of PIRADS alone, PIRADS and PSAD, PIRADS and ADC, PIRADS, PSAD and ADC using the AUC to discriminate a positive histological prostate caseResults: PIRADS had AUC 0.70, combination of PIRADS V2.1 and PSAD had AUC 0.73, combination of PIRADS, PSAD and ADC had AUC 0.72Impact: PIRADS accurately predicts PCa satisfactorily AUC 70%. It may be used in an African population in combination with clinical information and history. This is because they were some cases graded as PIRADS 2 and yet had a high gleason score.