Comparative value of free-breathing DCE-MRI based on GRASP and conventional BH-VIBE sequence in evaluating the image quality in lung cancer

Motivation: Dynamic Contrast Enhancement-CT (DCE-CT) and Dynamic Contrast Enhancement-MRI (DCE-MRI) are among the most valuable imaging techniques for the noninvasive assessment of tumor vascular perfusion and trophoblast angiogenesis in lung cancer. Goal(s): To evaluate the image quality value of free-breathing GRASP in MRI of lung cancer. Approach: All patients underwent free-breathing DCE-MRI with breath-holding VIBE sequence before and after contrast injections. Two experienced thoracic radiologists independently evaluated the overall image quality, lesion contour, artifact level, and diagnostic confidence using the patient's simultaneous CT images as a reference. Results: Free-breathing GRASP DCE-MRI technique is a reliable method for the high-resolution imaging of pulmonary lesions. Impact: The study showcases GRASP's superiority over BH-VIBE in lung cancer imaging, offering clearer results with patient comfort. This breakthrough prompts investigation into GRASP's broader clinical applications and sets a new standard in patient-friendly MRI diagnostics.