Fast Quantitative T1, T2, PD, B1 and QSM Mapping Using A Single MR Fingerprinting Acquisition And A Phase-Sensitive Deep Reconstruction Network.

Motivation: Incorporating MR phase into the MRF scheme can provide further diagnostic information, such as QSM. However, the MRF dictionary exponentially grows with the number of parameters to estimate. Goal(s): To validate QSM and B1 mapping using MRF and PS-DRONE reconstruction network against conventional reference maps. Approach: Data were acquired at 3T with an EPI-MRF, a multi-echo GRE sequence for QSM and a Bloch Siegert sequence for B1 mapping. Results: PS-DRONE enabled simultaneous quantification of T1, T2, PD, B1 and maps in 2 minutes. Tissue parameter maps were reconstructed in 1 second. Strong correlations were observed to reference B1 and QSM maps. Impact: The ability of PS-DRONE to quantitatively image T1, T2, PD, B1 and QSM with similar accuracy to conventional techniques, but in a fraction of the time, would promote the use of multiparametric quantitative MRI in clinical practice.