Autonomic Regression in fMRI during Alertness: Insights from Respiration, Pupil Size, and PPG Amplitude

Motivation: Understanding autonomic regulation during a cognitive task is vital for unraveling its neural mechanisms. This study delves into autonomic regression in fMRI, examining the roles of respiration, pupil size, and PPG amplitude during alertness. Goal(s): Our goal is to enhance our understanding of the autonomic nervous system's response to alert conditions by analyzing fMRI data and modeling with various physiological signals. Approach: Through the examination of respiration, pupil size, and PPG amplitude and fMRI, we aim to reveal patterns of autonomic regression. Results: The results uncover significant associations between autonomic parameters and fMRI, shedding light on the neuro-physiological correlates of cognitive stress. Impact: Our findings advance strategies for managing systemic variations during alert conditions, providing valuable insights for fMRI researchers.