3D Isotropic Wideband LGE for Supporting Ventricular Tachycardia Ablation in Patients with an Implantable Cardioverter Defibrillator

Motivation: Catheter ablation is clinically indicated for targeting re-entrant ventricular tachycardia (VT) in patients with an implantable cardioverter defibrillator (ICD), but its 1-year VT recurrence rate is high. We hypothesize that 3D wideband LGE is useful for guiding VT ablation. Goal(s): To determine whether 3D wideband LGE correlates with electroanatomic mapping (EAM) in ICD patients. Approach: To develop a 3D isotropic wideband LGE pulse sequence and validate it against EAM in ICD patients. Results: While myocardial scars and gray-zones in LGE correlated with the low voltage areas (<1.5 mV) in EAM, mid-myocardial non-ischemic scars was not correlated between LGE and EAM. Impact: High-resolution 3D isotropic wideband LGE has potential to increase the success rate of catheter ablation for re-entrant ventricular tachycardia in patients with an implantable cardioverter defibrillation, as well as decrease the procedural time by providing a roadmap prior to ablation.