Submillimeter Whole-Brain VASO fMRI using a View-Sharing with Temporal Random Walk at 7 Tesla

Motivation: Cerebral blood volume (CBV) fMRI has inherent limitations regarding its imaging efficiency, restricting the spatial volume coverage and spatiotemporal resolutionGoal(s): To improve imaging efficiency for whole-brain VASO fMRI with high temporal resolutionApproach: we introduce a view sharing approach combined with flexible temporal encodingResults: Proposed method achieves whole-brain VASO and BOLD imaging in 8.3 seconds, while resulting in higher VASO and BOLD activations with high sensitivityImpact: We confirmed that 1) a view-sharing approach allows VASO and BOLD signal detection without contrast confounding and 2) the random encoding coupled with view sharing significantly improves the imaging efficiency by achieving an 8.3 second whole-brain VASO imaging.