Evaluating 0.55T FISP MRF using EPG-X Formalism

Motivation: MT effects influence MRF T1 and T2 quantifications and are stronger at lower field strength. Goal(s): To evaluate the impact of EPGx dictionary generation on relaxometry performance for 0.55T FISP MRF. Approach: We applied the EPG-X formalism with a two-pool model which incorporates MT parameters for dictionary simulation for 0.55T FISP MRF and covered a range of realistic MT parameters values. We applied the approach on 4 healthy subjects. Results: Use of EPGx reduced T2 bias (compared to single-echo spin echo) by 25% at a cost of 80% worse precision. Impact: Simulating dictionary using the EPG-X formalism with a two-pool model can partially mitigate MT effects and may reduce T2 bias.