Push-button liver DCE MRI: free-breathing, high-resolution 3D DCE with T1 mapping using multitasking joint reconstruction

Motivation: To address the pain points in clinical abdomen DCE, including sacrifice of spatial resolution for temporal resolution, repeated breath-hold, risk of missing contrast arrival, and the need for separate T1 mapping scan. Goal(s): To develop an all-in-one, push-button abdomen DCE technique that improves kinetic mapping. Approach: It was developed using MR multitasking joint reconstruction and tested on volunteer and phantom. Results: Its feasibility was proven. Its feature includes free-breathing, high spatial and temporal resolution, and embedded T1 and B1 mapping for kinetic modeling correction. Impact: Abdomen DCE with the proposed MR multitasking joint reconstruction approach can make clinical liver DCE more accessible, more accurate and hassle-free, allowing further researches on DCE in liver disease diagnosis.