MRI meets economics: Balancing sample size and scan duration
Motivation: Resting-state functional connectivity (RSFC) is widely used to predict behavioral traits in individuals. Goal(s): A pervasive dilemma when collecting functional MRI data is whether to prioritize sample size or scan duration given fixed resources. Approach: We systematically investigate the trade-off between sample size and scan time in the context of prediction accuracy and reliability of brain-behavior relationships using RSFC. Results: Increasing sample size (with fixed scan time) or scan time (with fixed sample size) leads to similar accuracy. Reliability of brain-behavior association can only be improved with bigger sample sizes but not scan time. Impact: Our findings establish an empirically informed reference for calibrating scan times and sample sizes to maximize prediction of behavioral performance and reliability of brain-behavior associations when using resting-state functional connectivity.
Authors
- Simon Bodo Eickhoff (ORCID: https://orcid.org/0000-0001-6363-2759)
- B.T. Thomas Yeo (ORCID: https://orcid.org/0000-0002-0119-3276)
- Nico U.F. Dosenbach (ORCID: https://orcid.org/0000-0002-6876-7078)
- Shaoshi Zhang (ORCID: https://orcid.org/0000-0002-6352-9150)
- Trevor Wei Kiat Tan (ORCID: https://orcid.org/0000-0002-3732-4768)
- Csaba Orbán (ORCID: https://orcid.org/0000-0001-9133-3561)
- Juan Helen Zhou (ORCID: https://orcid.org/0000-0002-0180-8648)
- Leon Qi Rong Ooi (ORCID: https://orcid.org/0000-0002-3546-4580)
- Scott Marek (ORCID: https://orcid.org/0000-0003-0032-9052)
- Danilo Bzdok (ORCID: https://orcid.org/0000-0003-3466-6620)
- Evan M. Gordon (ORCID: https://orcid.org/0000-0002-2276-5237)
- Thomas E. Nichols (ORCID: https://orcid.org/0000-0002-4516-5103)
- Ru Kong (ORCID: https://orcid.org/0000-0001-7842-0329)
- Timothy O. Laumann
- Avram J. Holmes (ORCID: https://orcid.org/0000-0001-6583-803X)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/0317
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00