The quantitative parameters based on IVIM andDCE-MRI in predicting the efficacy in patients with nasopharyngeal carcinoma

Motivation: This study aims to establish a predictive model based on IVIM and DCE-MRI that could ultimately improve the prognosis of nasopharyngeal carcinoma (NPC) patients. Goal(s): This research paves the way for more effective and tailored treatment approaches for NPC patients. Approach: Patients in the CR group and the NCR group underwent IVIM and DCE-MRI experiments and their quantitative parameters were compared. Results: The CR group exhibited higher Ktrans value and lower D and ADC values compared to the NCR group. ROC analysis showed that the AUC values of Ktrans, D and ADC before treatment were approximately 0.772, 0.751, and 0.699, respectively. Impact: Early prediction of the efficacy of NPC patients can optimize the treatment plans, functional MRI techniques can offer insights into the pathological and physiological state of living tissues before morphological changes, prolong their survival, and hold immense clinical significance.