Advancing Brain Tumour Sodium Imaging: Prospectively Accelerated eSISTINA and Compressed Sensing at 7T

Motivation: Leverage cutting-edge enhanced simultaneous single and triple quantum filtered sodium imaging sodium imaging (eSISTINA) at 7T for unparalleled image precision, enhancing diagnostic efficacy and pushing the clinical frontier in brain tumour analysis. Goal(s): Optimise imaging and relaxometry performance of the eSISTINA sequence without compromising clinically applicability due to exessive measurement times. Approach: FLORET spiral trajectories coupled with pseudo-randomised undersampling and compressed sensing reconstruction yield significantly enhanced image quality and relaxometry performance of eSISTINA. Results: Compressed sensing reconstructed images of a brain tumour patient highlight substantial improvements in quality and aquicistion efficiency of eSISTINA at 7T, surpassing prior work at lower field strengths. Impact: This study demonstrates clearly that eSISTINA at ultra-high field strength is a promising diagnostic tool, offering invaluable insights for clinicians and researchers. Future patient cohort studies will undoubtedly reveal novel perspectives on brain tumours and metabolism.