Simultaneous Multiparametric Quantitative MRI for Abdominal Imaging in a Single Breath-hold with MRF-EPTI

Motivation: Multiparametric mapping is essential in the assessment of renal physiology and physiopathology, while the conventional quantitative MR methods requires long acquisition time and multiple breath-hold periods. Goal(s): To develop an efficient simultaneous multiparametric quantification method for abdomen imaging. Approach: MRF-EPTI technique was applied for quantitative abdomen imaging. The repeatability was evaluated by in-vivo scans on two healthy volunteers. Motion sensitivity was evaluated with/without breath-hold. Results: Simultaneous multiparametric quantification of T1, T2, T2*, proton density and quantitative susceptibility mapping including susceptibility source separation for abdominal imaging was achieved in a single breath-hold time (16s). Impact: We acquired simultaneous multiparametric quantification of T1, T2, T2*, proton density and quantitative susceptibility mapping including susceptibility source separation, and generated high-quality multi-contrast synthetic images for abdominal imaging in a single breath-hold with MRF-EPTI technique.