Anatomy of neo-aorta can cause abnormal flow patterns

Motivation: The descending aorta (DAo) in patients with hypoplastic left heart syndrome (HLHS) after Norwood procedure is frequently enlarged although this region is not subject to surgical procedures. Goal(s): The aim of this study is to investigate whether the aortic anatomy can cause abnormal flow patterns which are related to vascular alterations. Approach: Based on anatomic models and flow boundaries from 4D flow MRI, we studied fluid-dynamics using CFD simulations. Results: We found increased vorticity and wall-shear stress in the HLHS descending aorta. Increased wall shear stress has been associated with the development of dilation and may explain vascular alterations in the descending aorta. Impact: This study gives motivation for further investigations and may ultimately lead to future Norwood procedure modifications.