Investigation of the methionine uptake of glioma cells through deuterium magnetic resonance spectroscopy
Motivation: Glioma tumor cells have abnormally higher uptake of methionine, compared to normal brain tissues. Goal(s): To characterize the methionine preference of glioma cells through deuterium magnetic resonance spectroscopy. Approach: Deuterium magnetic resonance spectroscopy in glioma C6 and CTX-TNA2 glial cells incubated by [1-2H3]-methionineResults: Abnormal uptake of deuterated methionine in glioma cells was revealed by using magnetic resonance deuterium spectroscopy, compared to normal cellsImpact: Deuterium magnetic resonance imaging with deuterium labeled methionine may have the potential in accurate diagnosis and treatment assessment of glioma.
Authors
- Chao Zou (ORCID: https://orcid.org/0000-0002-6387-7809)
- Qian Wan (ORCID: https://orcid.org/0000-0001-9243-8939)
- Xin Liu (ORCID: https://orcid.org/0000-0001-9075-7207)
- Hairong Zheng
- Peng Hao (ORCID: https://orcid.org/0000-0002-5239-4991)
- Guangyan Yang (ORCID: https://orcid.org/0000-0003-4498-5844)
- Junyi Duan (ORCID: https://orcid.org/0000-0003-3402-5890)
- Ye Li (ORCID: https://orcid.org/0009-0002-5183-2723)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/3057
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 0.00