Predictive values of structural and functional magnetic resonance on neurological improvement in pediatric spinal cord injury

Motivation: Are the different prognosis of pediatric spinal cord injury (SCI) patients related to differences in brain structure and function? The research on this project has a good guiding significance for prognosis prediction and advanced intervention treatment.Goal(s): To search for sensitive imaging indicators that can predict neurological outcomes in pediatric SCI patients.Approach: Voxel-based morphometry (VBM) and fractional amplitude of low-frequency fluctuations (fALFF) were used to analyze the differences of brain structure and function in children with and without neurological improvement.Results: The medial temporal gyrus may be used as neuroimaging biomarker to predict the prognosis of pediatric SCI.Impact: MTG can be used as neuroimaging biomarker to predict the prognosis of children with SCI , providing imaging support for clinical stimulation of related brain regions to improve the probability of neurological improvement.