Liver T1 Mapping in a Large Cohort of Healthy Subjects: Normal Ranges and Correlation with Age and Sex
Motivation: To fully exploit the clinical potential of T1 mapping in liver disease detection, normal values should be established. Goal(s): We defined normal ranges for native hepatic T1 values using a 1.5T General Electric scanner. Approach: MOLLI sequences were acquired in 100 healthy volunteers and native T1 values were quantified in the visible hepatic segments. Results: Segmental and global liver T1 values exhibited a good intra- and inter-observer reproducibility. A significant difference in the segmental T1 values was detected. Segmental and global T1 values were not associated with age and were comparable between males and females. Impact: Liver T1 mapping is feasible and reproducible and the provided normal ranges may help to establish diagnosis and progression of various liver diseases.
Authors
- Antonella Meloni (ORCID: https://orcid.org/0000-0002-2284-8585)
- Melchiore Giganti (ORCID: https://orcid.org/0000-0002-5319-8685)
- Alessia Pepe (ORCID: https://orcid.org/0000-0001-6401-3829)
- Filippo Cademartiri (ORCID: https://orcid.org/0000-0002-0579-3279)
- Giancarlo Todiere (ORCID: https://orcid.org/0000-0002-3459-026X)
- Chrysanthos Grigoratos (ORCID: https://orcid.org/0000-0002-8097-9081)
- Aldo Carnevale (ORCID: https://orcid.org/0000-0001-8191-6042)
- Petra Keilberg
- Alberto Cossu (ORCID: https://orcid.org/0000-0002-3462-1695)
- Laura Pistoia (ORCID: https://orcid.org/0000-0002-5319-2769)
- Andrea Barison (ORCID: https://orcid.org/0000-0001-9042-340X)
- Vincenzo Positano (ORCID: https://orcid.org/0000-0001-6955-9572)
- P. Gaio
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/0837
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00