Influence of hepatic steatosis on T1 values of the liver: Comparison of T1 mappings at different echo times

Motivation: In evaluating T1 values in patients with hepatic steatosis, it is necessary to investigate the effect of fat because MOLLI is sensitive to fat. Goal(s): To elucidate the clinical importance of MOLLI T1 mapping of the liver using TE=1.8 (AIOP) sequence in daily practice. Approach: In 122 patients with suspected liver diseases, MOLLI T1 mapping with TE=1.8 (AIOP) was compared with that with TE=1.3 (OP) and TE=2.4 (IP). Results: The positive correlation with high correlation coefficient between T1 value of the liver in AIOP sequence and FIB-4 score was observed in patients with hepatic steatosis (PDFF ≥10%). Impact: T1 mapping using AIOP sequence will be critical for assessing liver fibrosis in patients with hepatic steatosis since T1 mapping obtained by OP and IP sequences have risk of over- and under-estimation of T1 measurements.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/0839
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Influence of hepatic steatosis on T1 values of the liver: Comparison of T1 mappings at different echo times

Mayumi Higashi, Masahiro Tanabe, Yosuke Kawano, Katsuyoshi Ito
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Liver Disease Diagnosis and Treatment
article

Influence of hepatic steatosis on T1 values of the liver: Comparison of T1 mappings at different echo times

Mayumi Higashi, Masahiro Tanabe, Yosuke Kawano, Katsuyoshi Ito
article en

Abstract

Motivation: In evaluating T1 values in patients with hepatic steatosis, it is necessary to investigate the effect of fat because MOLLI is sensitive to fat. Goal(s): To elucidate the clinical importance of MOLLI T1 mapping of the liver using TE=1.8 (AIOP) sequence in daily practice. Approach: In 122 patients with suspected liver diseases, MOLLI T1 mapping with TE=1.8 (AIOP) was compared with that with TE=1.3 (OP) and TE=2.4 (IP). Results: The positive correlation with high correlation coefficient between T1 value of the liver in AIOP sequence and FIB-4 score was observed in patients with hepatic steatosis (PDFF ≥10%). Impact: T1 mapping using AIOP sequence will be critical for assessing liver fibrosis in patients with hepatic steatosis since T1 mapping obtained by OP and IP sequences have risk of over- and under-estimation of T1 measurements.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Good health and well-being
Openalex Percentile: Top 68%
Liver Disease Diagnosis and Treatment
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