Enhanced Lateralization of Mesial Temporal Lobe Epilepsy through Vascular Territory Analysis: Insights from Arterial Spin Labeling MRI

Motivation: To enhance lateralization of drug-resistant mesial temporal lobe epilepsy (mTLE) for improved surgery decisions. Using arterial spin labeling (ASL) MRI, this study explores vascular territories to differentiate left and right mTLE. Goal(s): To assess ASL MRI's potential in distinguishing between mTLE types by studying cerebral blood flow changes. Approach: It involves comparing mTLE groups to controls using ASL MRI and vascular territory analysis, identifying specific brain regions affecting lateralization. Results: They highlight vascular territory changes crucial in distinguishing mTLE types, emphasizing the clinical significance of ASL MRI. Impact: This research may significantly impact treatment decisions, benefitting individuals with challenging mTLE and guiding future epilepsy research.