Exploring the additive effects of hypertension on left cardiac structure and deformation in type 2 diabetes mellitus patients using CMR-FT

Motivation: Hypertension and type 2 diabetes mellitus (T2DM)-related cardiac damage have a partial common pathological mechanism[1]. Goal(s): To investigate the effects of hypertension on left cardiac structure and deformation in patients with T2DM using cardiac magnetic resonance feature tracking. Approach: The balanced steady-state free precession cine sequence and commercial software, cvi42, were used for image acquisition and post-processing. Covariance and multivariate linear regression were used for statistical analysis. Results: Hypertension has additive effects on left atrial and left ventricular geometry and strain in patients with diabetes. Impact: Our findings regarding the additive effect of hypertension in patients with diabetes provides a basis for clinical management and treatment of these comorbidities.