Liver T2 Mapping in a Large Cohort of Healthy Subjects: Normal Ranges and Correlation with Age and Sex

Motivation: To ensure successful integration of hepatic T2 mapping into clinical workflow it is critical to establish normal reference values. Goal(s): We defined normal ranges for hepatic T2 values using a 1.5T General Electric scanner. Approach: Multi-echo fast-spin-echo sequences were acquired in 100 healthy volunteers and T2 values were quantified in the visible hepatic segments. Results: Segmental and global liver T2 values exhibited a good intra- and inter-observer reproducibility. No significant regional T2 variability was detected. Global T2 values were not associated with aging but were significantly lower in males than in females. Impact: In healthy subjects liver T2 mapping is feasible and reproducible and T2 values are influenced by gender, suggesting the need for the use of normative values differentiated by gender.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/4153
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Liver T2 Mapping in a Large Cohort of Healthy Subjects: Normal Ranges and Correlation with Age and Sex

Antonella Meloni, Melchiore Giganti, Alessia Pepe, Filippo Cademartiri et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Liver Disease Diagnosis and Treatment
article

Liver T2 Mapping in a Large Cohort of Healthy Subjects: Normal Ranges and Correlation with Age and Sex

Antonella Meloni, Melchiore Giganti, Alessia Pepe, Filippo Cademartiri, Giancarlo Todiere, Chrysanthos Grigoratos, Aldo Carnevale, Alberto Cossu, Laura Pistoia, Andrea Barison, Vincenzo Positano, Cristina Passantino, P. Gaio, Gianni Novani
article en

Abstract

Motivation: To ensure successful integration of hepatic T2 mapping into clinical workflow it is critical to establish normal reference values. Goal(s): We defined normal ranges for hepatic T2 values using a 1.5T General Electric scanner. Approach: Multi-echo fast-spin-echo sequences were acquired in 100 healthy volunteers and T2 values were quantified in the visible hepatic segments. Results: Segmental and global liver T2 values exhibited a good intra- and inter-observer reproducibility. No significant regional T2 variability was detected. Global T2 values were not associated with aging but were significantly lower in males than in females. Impact: In healthy subjects liver T2 mapping is feasible and reproducible and T2 values are influenced by gender, suggesting the need for the use of normative values differentiated by gender.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Gender equality
Openalex Percentile: Top 68%
Liver Disease Diagnosis and Treatment
DOISourceOpenAlex
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