NeoAudi Tract: An Automated Tool for Identifying Auditory Fiber Bundles in Infants
Motivation: Charting the development of infant auditory system is vital for understanding language acquisition and hearing disorders. Goal(s): Extracting auditory fiber bundles from diffusion MRI data and overcoming the processing difficulties due to tiny and complex structures, as well as very low tissue contrast in the structural MRI data. Approach: We propose an NAT framework with three core processes: 1) constructing a high-resolution atlas, 2) segmenting tissues and regions of interest (ROIs), and 3) applying a hierarchical registration framework. Results: A high-resolution auditory fiber bundle template is constructed, and 12 auditory fiber bundles are successfully extracted. Impact: Our approach is the first toolbox to identify individual auditory fiber bundles in infants, thus effectively mitigating the processing challenges caused by spatial-temporal asynchrony during the development of the first two postnatal years.
Authors
- Dinggang G. Shen (ORCID: https://orcid.org/0000-0002-7934-5698)
- Junjun Feng (ORCID: https://orcid.org/0000-0001-6894-3361)
- Yuting Zhu (ORCID: https://orcid.org/0000-0002-0746-8533)
- Feng Shi (ORCID: https://orcid.org/0000-0002-2407-1239)
- Feihong Liu (ORCID: https://orcid.org/0000-0001-5199-5261)
- Zhaoyan Wang (ORCID: https://orcid.org/0000-0002-0977-0920)
- Rui Hua (ORCID: https://orcid.org/0000-0001-6686-6913)
- Yaoxuan Wang (ORCID: https://orcid.org/0000-0003-1002-7242)
- Mengda Jiang (ORCID: https://orcid.org/0000-0001-6046-7735)
- Jiawei Huang (ORCID: https://orcid.org/0000-0001-7670-2971)
- Jiameng Liu (ORCID: https://orcid.org/0000-0003-0146-0001)
- Jinchen Gu
- Han Zhang (ORCID: https://orcid.org/0009-0000-8542-2509)
- Hao Wu (ORCID: https://orcid.org/0009-0007-2765-5161)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/0240
- Citations
- 1
- Primary Topic
- Hearing Loss and Rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 0.34