Alterations in the Pain-Related Functional Matrix among RCVS Patients during Resting-State fMRI.

Motivation: Reversible cerebral vasoconstriction syndrome (RCVS) is a severe headache condition marked by recurrent explosive headaches. We investigate changes in the functional connectivity of brain regions associated with pain matrix in both RCVS patients and healthy controls. Goal(s): Our hypothesis the functional connectivity mechanisms underlying pain processing differ between two groups. Approach: We utilizing rs-fMRI imaging with graph theory analysis. Results: The findings contribute to a more profound comprehension of the activation processes occurring within brain regions responsible for pain perception RCVS patients.We ascertain whether the mechanisms of pain processing in RCVS patients deviate from those observed in healthy controls. Impact: We utilizing rs-fMRI imaging with graph theory to investigate functional connectivity mechanisms of pain matrix. The findings contribute comprehension of the activation processes occurring within brain regions responsible for pain perception RCVS patients deviate from those observed in healthy controls.