Feasibility of a 2D Radial Simultaneous Multi-Slice Phase Contrast MRI sequence for Aortic Pulse Wave Velocity Measurements

Motivation: Pulse wave velocity (PWV) is an important biomarker for cardiovascular risk that can be measured non-invasively with phase contrast MRI. Sequential scans at different planes can lead to inaccurate measurements so an alternate approach is needed. Goal(s): We aim to develop a 2D simultaneous multi-slice (SMS) radial phase contrast sequence to image multiple planes concurrently, reduce timing inconsistencies, and measure PWV more accurately. Approach: The radial phase contrast SMS sequence was implemented on a GE scanner and included in an ongoing volunteer study. Results: The SMS scan provided higher quality images in less scan time than sequential and had reduced timing inconsistencies. Impact: Pulse wave velocity (PWV) is a clinically important biomarker for cardiovascular risk. A simultaneous multi-slice radial 2DPC sequence allows for faster, more accurate MR flow measurements with high temporal resolution and reduced timing inconsistency which can improve early detection.