Value of intravoxel incoherent motion diffusion-weighted MRI in evaluating endometrial receptivity in women with polycystic ovary syndrome

Motivation: This study evaluated endometrial receptivity in women with polycystic ovary syndrome (PCOS) impacting embryo implantation and pregnancy outcomes. Goal(s): The primary objectives were to evaluate endometrial receptivity by measuring uterine junctional zone (UJZ) and myometrium parameters and to explore the correlation between these imaging parameters and hormonal levels. Approach: Using intravoxel incoherent motion (IVIM), the study measured the quantitative parameters of the UJZ and myometrium in women with PCOS. Results: Patients with PCOS had lower UJZ and myometrium f values than controls, indicating reduced perfusion affecting embryo implantation. A positive correlation with free thyroxine levels was observed. Impact: Intravoxel incoherent motion imaging is vital in assessing endometrial receptivity. Patients with polycystic ovary syndrome had lower f values of the uterine junctional zone and myometrium than controls, suggesting less blood perfusion, which might be associated with poor pregnancy outcomes.