Analysis of Generation of Arbitrary Spectral Profiles (GASP) for Water-Fat Separation

Motivation: This research explores using multiple bSSFP images to generate arbitrary spectral profiles for use in water-fat separationGoal(s): Our goal is to analyze the generation of synthetic spectral profiles and use this technique for water-fat separation. Approach: We use computational simulations to analyze the effectiveness of generating arbitrary spectral profiles for filtering different tissues and validate our technique with an in-vivo knee experiment. Results: Our experiments demonstrate that the banding artifacts from multiple bSSFP acquisitions with varying TRs and phase cycles can be used to spectrally isolate water from fat signals. Impact: Multiple bSSFP images can be linearly combined to generate arbitrary spectral profiles and isolate tissues for water-fat separation