Free-breathing Motion-Corrected Liver DWI at 3T with Optimized Fat-suppression Scheme

Motivation: A free-breathing motion-insensitive and high-quality DWI is desired for abdominal DWI in clinical practice. Goal(s): This study is to propose and evaluate a novel ss-EPI DWI sequence incorporating motion correction , complex averaging , and a combination of a reparametrized sinc fatsat pulse with an optimized water excitation pulse for abdominal DWI. Approach: Four different DWI sequecnes were performed on volunteers. The overall image qualities and the SNR on the liver papernchyma were evaluated and compared. Results: The SNRs of the liver and the image qualities were significantly higher with the proposed Free-breathing motion-corrected DWI ( MOCO-DWI ) sequence compared to other EPI DWI sequences. Impact: The free-breathing MOCO-DWI sequences with complex-averaging and new fat suppression scheme is recommended for high-quality liver DWI in clinical routine.