Association between Paravertebral Muscle Radiological Parameters Alterations and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study

Motivation: This study aims to assess the alterations in skeletal muscle parameters in patients with histologically confirmed NAFLD. Goal(s): Find a non-invasive method for the diagnosis of NASH from NAFLD. Approach: The data were analyzed using SPSS 26.0 statistical software. Results: Our findings revealed a positive correlation was observed between NAS scores and the FIR of MF muscle at the L3 level. Remarkably, MF muscle fat infiltration and ALT emerged as independent risk factors for NASH. Moreover, the integration of laboratory indices and radiological parameters in a combined model shows promising potential for the diagnosis of NASH. Impact: This study has revealed a profound association between PVM muscle radiological parameters and the severity of NAFLD and provided novel avenues for the diagnosis of NASH.