Cortical Sulcus Depth Alterations in Patients with Tinnitus Before and After Sound Therapy: A Surface-Based Morphometry Study

Motivation: This study aimed to explore alterations in brain surface-based morphometry sulcal depth in patients with idiopathic tinnitus before and after 24 weeks of sound therapy. Goal(s): This study aimed to explore alterations in brain surface-based morphometry sulcal depth in patients with idiopathic tinnitus before and after 24 weeks of sound therapy. Approach: Thirty-three tinnitus patients underwent magnetic resonance imaging scans at baseline and after 24 weeks of sound therapy. Results: Compared to HCs, those in the tinnitus group at baseline had significantly lower sulcal depth in the left medial temporal cortex (MTC) and right somatosensory and motor cortex (SMC). Impact: The remodeling of sulcal depth after sound therapy is an indicator for effective sound therapy.