The Value of Multimodal Atherosclerotic Plaque Imaging Coordinated Analysis in the Assessment of Cardiovascular and Cerebrovascular Events

Motivation: The coexistence of atherosclerosis in coronary, and intracranial arteries has not been comprehensively assessed. Goal(s): This study was designed to investigate the co-existence of atherosclerosis in the intracranial and coronary arteries of patients with and without ASCVD using high-resolution magnetic resonance imaging and computed tomography angiography. Approach: The ASCVD group exhibited greater artery stenosis, as well as significant differences in lipid, calcium volumes, and lipid volume ratio compared to the non-event group. Additionally, different plaque types displayed significant variations in morphology and composition. Results: There is a consistent pattern of change in plaque characteristics between intracranial and coronary arteries. Impact: High-resolution magnetitic resonance imaging (hrMRI) and coronary computed tomography angiography (CCTA) to investigate the co-existence of high-risk atherosclerotic plaques in the intracranial and coronary arteries of patients with cardiovascular events. Results showed that such plaques were present in both locations.