Silent resting-state fMRI using Looping Star Multi-echo acquisition in a 3T high-performance gradient (300 mT/m & 750 T/m/s) MRI system (MAGNUS)
Motivation: To leverage the intrinsic multi-echo capabilities of Looping Star (ME-LS) for fMRI applications to minimize susceptibility-related signal loss to enhance sensitivity to underlying neurovascular changes. Goal(s): Our objective is to demonstrate feasibility of detecting resting state networks using a silent multi-echo fMRI approach enabled by Looping StarApproach: Resting-state Multi-echo Looping Star fMRI was implemented on MAGNUS and scanned in healthy volunteers. Results: This feasibility study shows established resting-state networks and connectome matrixes for multi-echo Looping Star fMRI and highlights the impact of the broad parameter space accessible with MAGNUS for Looping Star. Impact: Silent ME-fMRI has a multitude of advantages, ranging from increased sensitivity to neuro-correlates of sleep dysregulation, auditory-sensory studies, neurological disorders and to provide a more immersive experience by combining sound with visual stimuli in the MR environment.
Authors
- Maureen N. Hood (ORCID: https://orcid.org/0000-0002-6111-9262)
- Thomas Foo (ORCID: https://orcid.org/0000-0002-9016-1005)
- Florian Wiesinger (ORCID: https://orcid.org/0000-0002-5597-6057)
- Angeliki Pollatou (ORCID: https://orcid.org/0000-0003-0379-4187)
- Vincent B. Ho (ORCID: https://orcid.org/0000-0001-6603-8384)
- Luca Marinelli (ORCID: https://orcid.org/0000-0001-7775-5952)
- Nastaren Abad (ORCID: https://orcid.org/0000-0002-7020-0492)
- Brice Fernandez (ORCID: https://orcid.org/0000-0002-8693-2313)
- Isabelle Heukensfeldt Jansen (ORCID: https://orcid.org/0009-0004-6490-4882)
- Ana Beatriz Solana (ORCID: https://orcid.org/0000-0002-7390-0101)
- J. Kent Werner (ORCID: https://orcid.org/0000-0001-9858-2931)
- Afis Ajala (ORCID: https://orcid.org/0000-0002-1763-0274)
- J. Kevin DeMarco (ORCID: https://orcid.org/0000-0001-6434-0010)
- Gail Kohls
- H Doug Morris
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/3306
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00