Differentiation of cardiac inflammatory diseases by myocardial cine T2 mapping

Motivation: Development of a non-contrast differential method for cardiac inflammatory diseaseGoal(s): Accurate identification of cardiac sarcoidosis and myocarditisApproach: Cardiac cine imaging to project T2 values using T2prep-based T2 mapping with dynamic multiple trigger-delay frameworkResults: Diastolic cine T2 values (54.2msec.) discriminated cardiac sarcoidosis from myocarditis with an AUC of 0.879, sensitivity of 86%, and specificity of 77%. Impact: This method is a new technique that captures changes in myocardial properties during the cardiac cycle without the use of contrast media.