The impact of nonlinear blood behavior on hemodynamic parameters in large vessels: more than expected

Motivation: It has not been exhaustively studied how the nonlinear behavior of the blood impacts the estimation of hemodynamic parametersGoal(s): To demonstrate the impact of nonlinear viscosities produced by diseases such as anemia and polycythemia on the estimation of hemodynamic parametersApproach: Hemodynamic parameters were estimated from synthetically generated 4D Flow images obtained from CFD simulations of the aorta using a nonlinear model for the viscosity and different levels of nonlinearityResults: Important differences were observed in WSS, OSI, and energy loss estimated using a nonlinear model for the viscosity compared to results obtained using constant viscosities. Comparisons were made for several casesImpact: This investigation could impact how the MR community estimate hemodynamic parameters from 4D MR images.