T1 and T2 of the Human Brain at 64 mT: Measurement of 20 Participants

Motivation: To enable quantitative techniques at low-field, it is necessary to establish expected T1 and T2 values within the brain for healthy adults. Goal(s): To measure and compare T1 and T2 of the healthy human brain at 64mT. Approach: 20 healthy volunteers were imaged at 64mT. The resulting images were segmented using SynthSeg, and average values for T1 and T2 were computed over gray matter, white matter, and cerebrospinal fluid regions. Results: Mean T1 and T2 were determined. Partial volume effects may limit the accuracy of the image segmentation and lead to large variations in gray matter and cerebrospinal fluid measurements. Impact: To establish normative values for quantitative MRI at low field, 20 healthy individuals were scanned at 64 mT. T1 and T2 are reported for gray matter, white matter, and cerebrospinal fluid.