Normative growth models for T2w 0.55T fetal brain and body MRI: population-averaged 4D atlases and volumetry centiles
Motivation: Low field MRI is a promising direction for fetal imaging. Yet, there are no reported models of fetal development specific to 0.55T. Goal(s): We aim to formalise normal fetal growth models for structural 0.55T MRI. Approach: We use registration-based approach for generation of spatio-temporal templates from 3D D/SVR reconstructed images of the fetal brain and body and apply deep learning segmentation to parcellate organs for volumetry from >100 control subjects. Results: This work introduces the first T2w fetal atlases and volumetry growth charts for 0.55T brain and body MRI depicting normal development across 22-38 weeks gestation. All models are publicly available online. Impact: This work is the first step toward formalisation of analysis protocols for normal fetal brain and body development and optimisation of segmentation methods for low field strength fetal MRI.
Authors
- Jacqueline Matthew (ORCID: https://orcid.org/0000-0003-4754-0322)
- Maria Deprez (ORCID: https://orcid.org/0000-0002-2799-6077)
- Megan Hall
- Sarah McElroy (ORCID: https://orcid.org/0000-0002-4271-5931)
- Aysha Luis (ORCID: https://orcid.org/0000-0001-5493-099X)
- Alena Uus (ORCID: https://orcid.org/0000-0001-5796-2145)
- Jana Hutter (ORCID: https://orcid.org/0000-0003-3476-3500)
- Kelly Payette (ORCID: https://orcid.org/0000-0001-7041-0150)
- Jordina Aviles Verdera (ORCID: https://orcid.org/0009-0007-7575-4244)
- Mary Rutherford (ORCID: https://orcid.org/0000-0003-3361-1337)
- Joseph V. Hajnal (ORCID: https://orcid.org/0000-0002-2690-5495)
- Kathleen Colford (ORCID: https://orcid.org/0000-0001-6501-8867)
- Lisa Story (ORCID: https://orcid.org/0000-0001-9328-9592)
- Sara Neves Silva (ORCID: https://orcid.org/0009-0009-7520-081X)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/0819
- Citations
- 1
- Primary Topic
- Fetal and Pediatric Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.11