Prenatal fat-water MRI-based body composition reference charts and sexual dimorphism
Motivation: Preterm infants’ nutritional management should aim to replicate the intrauterine body composition. However, intrauterine body composition reference charts are lacking. Goal(s): We aimed to construct MRI-based intrauterine body mass (BM), fat mass (FM), percent FM (%FM), fat-free mass (FFM), and percent FFM (%FFM) body composition reference charts. Approach: Fetal body composition was computed from T2-weighted and fat-water images. Body and subcutaneous fat volumes were automatically segmented using neural networks, and BM, FM, %FM, FFM, and %FFM were calculated. Results: Data of 176 participants with apparently normal singleton fetuses were included. All parameters significantly changed throughout gestation, and differences between sexes were seen. Impact: MRI-based intrauterine BM, FM and FFM body composition reference charts may be used as reference for appropriate prenatal growth and may assist in nutritional management of preterm infants.
Authors
- Bella Specktor‐Fadida (ORCID: https://orcid.org/0000-0002-5668-0303)
- Bossmat Yehuda (ORCID: https://orcid.org/0000-0002-5506-1498)
- Aviad Rabinowich (ORCID: https://orcid.org/0000-0002-9406-6523)
- Leo Joskowicz (ORCID: https://orcid.org/0000-0002-3010-4770)
- Jacky Herzlich (ORCID: https://orcid.org/0000-0001-8999-6841)
- Dafna Ben Bashat (ORCID: https://orcid.org/0000-0001-8396-1031)
- Bar Neeman (ORCID: https://orcid.org/0009-0008-4806-2979)
- Liat Ben‐Sira (ORCID: https://orcid.org/0000-0002-0827-0190)
- Liran Hiersch (ORCID: https://orcid.org/0000-0003-4443-388X)
- A. Zilberman (ORCID: https://orcid.org/0000-0002-7860-2605)
- Netanell Avisdris (ORCID: https://orcid.org/0000-0002-0719-1327)
- Sharon Klein
- Tamir Graziani
- Jayan Khawaja
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/0820
- Primary Topic
- Body Composition Measurement Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00