Multimodal MRI Evaluation of Brain Plasticity Following 8 Weeks of Structured Functional and Strength Training

Motivation: The impact of longer exercise durations and its correlation with comprehensive behavioral changes, such as improvements in strength and working memory, remains relatively underexplored. Goal(s): In this study, we explore the impact of an 8-week strength training program on brain function and structure through multimodal MRI. Approach: We recruited 21 participants, who had been leading a sedentary lifestyle before enrolling. Utilizing a Siemens Prisma scanner and Human Connectome Project protocols, we obtained multimodal MRI data, covering anatomical scans, diffusion imaging, resting state fMRI, and ASL scans. Results: Preliminary findings highlight the importance of microstructural measurements in detecting exercise-induced brain changes. Impact: This research highlights the potential for using multimodal MRI to characterize exercise-induced white matter plasticity in the brain, particularly in motor-related areas.