The Feasibility of Analyzing Systolic and Diastolic Myocardial Volume Ratio Based on CMR to Evaluate Myocardial Fibrosis in HCM Patients

Motivation: CMR, the gold standard for diagnosing myocardial diseases, is known for its ability to assess local myocardial fibrosis through LGE imaging. However, this imaging technique requires a contrast agent, limiting its use in patients with allergies or renal dysfunction. Goal(s): The purpose of this study is to assess the ability of MVs/MVd as a new indicator to measure the extent of myocardial fibrosis. Approach: Explore the correlation between MVs/MVd and LGE% in patients with hypertrophic cardiomyopathy. Results: The results indicate that MVs/MVd may possess the ability to indicate myocardial fibrosis without the need for a contrast agent. Impact: MVs/MVd, in contrast to traditional methods, directly measures the entire cardiac cycle, offering valuable insights into myocardial properties. Importantly, it can gauge myocardial fibrosis to some extent without requiring a contrast agent, making it clinically significant for diagnosis and treatment.