Radiomic Features of Placental Magnetic Resonance Imaging Identify Adverse Pregnancy Outcomes: A Pilot Study

Motivation: Chronic hypertension (cHTN) is a significant obstetric condition with increased risk of adverse outcomes. Radiomic analysis of MR images may be able to predict outcomes before development of clinical findings. Goal(s): Our goal was to compare MR T2W radiomic features among 4 clinical outcomes: normal, cHTN, preeclampsia with severe features, and small for gestational age (SGA). Approach: We applied ROI-based radiomics analysis on prospectively collected T2W MR images in normal and cHTN pregnancies. Results: We found that MR T2W radiomic features as early as 16 weeks can identify those patients who develop preeclampsia with severe features and whose infants are born SGA. Impact: We demonstrated that MR T2W radiomic features as early as 16 weeks can identify those patients who develop preeclampsia with severe features and whose infants are born small for gestational age.