Evaluating the Diagnostic Efficacy of Cardiac MRI Quantitative Imaging Parameters in Hypertensive Heart Disease During Compensation

Motivation: Early detection of hypertensive heart disease (HHD) in the compensatory stage is clinically challenging, necessitating novel evaluative parameters for cardiac function alterations due to HHD. Goal(s): This research aimed to ascertain the diagnostic value of multiparametric cardiac magnetic resonance (CMR) imaging in this phase. Approach: We compared cardiac functional parameters, T1 mapping, extracellular volume fraction (ECV), and myocardial strain metrics obtained via CMR among compensatory HHD, decompensated HHD, and a normotensive control group. Results: Findings reveal that both circumferential and longitudinal strains in the compensatory HHD cohort were significantly reduced compared to the control group (P<0.05). Impact: Employing quantitative CMR parameters facilitates the assessment of myocardial functional impairments in hypertensive heart disease, potentially unmasking subclinical cardiac dysfunction and providing prognostic value for disease progression.