Distinguishing early liver fibrosis: integrating clinical and elastography features and radiomics signatures from Gd-EOB-DTPA-enhanced MRI

Motivation: Despite the effectiveness of elastography and serology tests in detecting liver fibrosis, diagnosing early-stage fibrosis remains challenging. Goal(s): Develop and validate a reliable radiomics model using Gd-EOB-DTPA-enhanced MRI for early liver fibrosis diagnosis. Approach: Create a radiomics model based on Gd-EOB-DTPA-enhanced MRI and establish a fused nomogram combining clinical characteristics and LSM. Compare the diagnostic performance of the fused model with single models for early-stage liver fibrosis. Results: Gd-EOB-DTPA-enhanced MRI radiomics model effectively diagnoses early liver fibrosis. The fusion model enhances diagnostic efficiency. Impact: To develop and validate a fusion model based on Gd-EOB-DTPA-enhanced MRI to identify early-stage liver fibrosis.